Specimen preparation 

To create a truly comprehensive sample-to-result assays, preparation of adequate volumes of clinical and environmental samples must be processed to extract and purify nucleic acids 

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Direct analysis of NP swabs for viruses, bacteria and host biomarkers 

There are simply too many viruses to identify the cause of an infection with conventional diagnostic technologies in a rapid and cost-acceptable fashion. 

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Direct analysis of wounds for infections 

Chronic wounds cause major humanitarian and economic burden in the United States. 

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Computational methods to identify, viruses, bacteria, host biomarkers 

Near patient or field-forward devices that analyze nanopore sequence data must interpret huge volumes of data, match with databases of microbes and present results in an actionable fashion. 

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Differential diagnosis of origin for Febrile Illness Using host response markers 

A rapid (<1 hr) point of care diagnostic test that accurately classifies the causative agent generating fever would reduce healthcare costs and save lives.

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Nanopore sequencing 

We believe that inexpensive nanopore sequencing will change the landscape of molecular diagnostics by enabling comprehensive analysis of clinical specimens in a commercially sustainable fashion with field-deployable instrumentation. 

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