To create a truly comprehensive sample-to-result assays, preparation of adequate volumes of clinical and environmental samples must be processed to extract and purify nucleic acids
Direct analysis of NP swabs for viruses, bacteria and host biomarkers
There are simply too many viruses to identify the cause of an infection with conventional diagnostic technologies in a rapid and cost-acceptable fashion.
Direct analysis of wounds for infections
Chronic wounds cause major humanitarian and economic burden in the United States.
Computational methods to identify, viruses, bacteria, host biomarkers
Near patient or field-forward devices that analyze nanopore sequence data must interpret huge volumes of data, match with databases of microbes and present results in an actionable fashion.
Differential diagnosis of origin for Febrile Illness Using host response markers
A rapid (<1 hr) point of care diagnostic test that accurately classifies the causative agent generating fever would reduce healthcare costs and save lives.
We believe that inexpensive nanopore sequencing will change the landscape of molecular diagnostics by enabling comprehensive analysis of clinical specimens in a commercially sustainable fashion with field-deployable instrumentation.